Key clinical beam parameters for nanoparticle-mediated radiation dose amplification
نویسندگان
چکیده
منابع مشابه
Key clinical beam parameters for nanoparticle-mediated radiation dose amplification
As nanoparticle solutions move towards human clinical trials in radiation therapy, the influence of key clinical beam parameters on therapeutic efficacy must be considered. In this study, we have investigated the clinical radiation therapy delivery variables that may significantly affect nanoparticle-mediated radiation dose amplification. We found a benefit for situations which increased the pr...
متن کاملA new method for ideal dose distribution of two adjacent fields for external beam radiation therapy
Abstract Background: Adjacent treatment fields are commonly used in external beam radiation therapy, such as mantle and inverted-Y fields for the treatment of Hodgkin’s disease and craniospinal fields used in the treatment of medulloblastoma and head and neck tumors when the lateral neck fields are placed adjacent to the anterior supraclavicular field. In each of these situations, there is a p...
متن کاملInfluence of concentration, nanoparticle size, beam energy, and material on dose enhancement in radiation therapy
The purpose of this study was to analyse the effects of the type, concentration, and nanoparticle diameter of dose enhancement materials on the dose enhancement of low- and high-energy megavoltage (MV) X-rays acquired from a medical linear accelerator using Monte Carlo simulation. Monte Carlo simulation was performed with the Monte Carlo N-Particle Transport (MCNPX) code, using the energy spect...
متن کاملNanoparticles for Radiation Therapy Enhancement: the Key Parameters
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It does not establish an exhaustive list of the works in this field but rather propose constructive criticisms pointing out critical factors that could improve the nano-radiation therapy. Whereas most reviews show the chemists and/or biologists points of view, the present analysis is also seen through the pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep34040